Article
Multicenter Validation of Clinical Sepsis Phenotypes.
JAMA network open - 1 Jun 2026
Yoon Chang Ho, Sjöholm Daniel, Wickstrøm Kristin E, Danielsen Anders Skyrud, Prebensen Christian, Valik John Karlsson, Holten Aleksander Rygh, Amundsen Erik Koldberg, Walker A Sarah, Eyre David W, Vitelli Valeria, Nauclér Pontus
Abstract excerpt
Importance: Four clinical phenotypes of sepsis based on data from electronic health records have been proposed. Although promising, the generalizability of these phenotypes remains uncertain, and multisite validation is needed. Objective: To validate, using the same methods and inclusion criteria, the 4 clinical phenotypes derived from Sepsis Endotyping in Emergency Care (SENECA) data. Design, Setting, and...
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