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A Dioxygenase Catalyzes Steroid 16α-Hydroxylation in Steroidal Glycoalkaloid Biosynthesis.

Plant physiology - 1 Sept 2017

Nakayasu Masaru, Umemoto Naoyuki, Ohyama Kiyoshi, Fujimoto Yoshinori, Lee Hyoung Jae, Watanabe Bunta, Muranaka Toshiya, Saito Kazuki, Sugimoto Yukihiro, Mizutani Masaharu

Abstract excerpt

Steroidal glycoalkaloids (SGAs) are toxic specialized metabolites that are found in the Solanaceae. Potato (Solanum tuberosum) contains the SGAs α-solanine and α-chaconine, while tomato (Solanum lycopersicum) contains α-tomatine, all of which are biosynthesized from cholesterol. However, although two cytochrome P450 monooxygenases that catalyze the 22- and 26-hydroxylation of cholesterol have been identified, the...

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PMID: 28754839
DOI: 10.1104/pp.17.00501
PMCID: PMC5580751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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