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Human norovirus GII genotypic diversity in Gwangju, South Korea, based on ORF1-ORF2 junction (RdRp-VP1) analysis from 2020 to 2024.

Scientific reports - 28 May 2026

Mun Jeongeun, Cho Sun-Ju, Seo Eunjin, Lee Ji-Eun, Lee Kwang Ho, Park Jeong Hee, Lee Yeong-Un, Kim HyeonJi, Seo Mihee, Gang Gyung-Li, Seo Jung-Mi, Park Jeongjin, Jun Woojin

Abstract excerpt

This study analyzed human norovirus genogroup II (GII) strains detected in Gwangju, South Korea, between 2020 and 2024, focusing on genetic diversity and recombination at the ORF1-ORF2 junction involving the RNA-dependent RNA polymerase (RdRp, ORF1) and the major capsid protein VP1 (ORF2). Using year-round surveillance-based clinical samples, the analysis revealed that recombination events near the ORF1-ORF2...

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PMID: 42209551
DOI: 10.1038/s41598-026-50533-y
PMCID: PMC13451207

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