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Article

Genotype frequency of Stargardt disease in Labrador Retrievers in Japan.

The Journal of veterinary medical science - 1 Aug 2026

Takanosu Masamine

Abstract excerpt

Canine Stargardt disease causes progressive retinal dysfunction leading to late-onset vision impairment and is inherited as an autosomal recessive trait. The causative mutation, c.4176insC in the ABCA4 gene, has been identified in Labrador Retrievers. This study investigated the genotype frequency of this mutation in Labrador Retrievers in Japan, providing the first estimate for this breed population. Genomic DNA...

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Identifiers

PMID: 42203465
DOI: 10.1292/jvms.25-0501
PMCID: PMC13500378

Genes

ABCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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