Article
Burst-Suppression EEG in Early Infantile Developmental and Epileptic Encephalopathies: Phenotype, Genotype, and Outcome.
Neurology - 23 Jun 2026
Riccardi Florence, Desnous Béatrice, Borloz Emilie, Lepine Anne, Lacoste Caroline, Mignon-Ravix Cécile, Cacciagli Pierre, Missirian Chantal, Molinari Florence, Mortreux Jérémie, Afenjar Alexandra, Altuzarra Cécilia, Auvin Stéphane, Bar Claire, Barth Magalie, Biscaye Stéphanie, Bourel-Ponchel Emilie, Cabasson Sébastien, Cances Claude, Castelnau Pierre, Caubel Isabelle, Carneiro Maryline, Chabrol Brigitte, Chadie Alexandra, Chaussenot Annabelle, Cheuret Emmanuel, Chouchane Mondher, Cogné Benjamin, Colin Estelle, Demurger Florence, Desportes Vincent, Dieux-Coeslier Anne, Doummar Diane, Goizet Cyril, Goldenberg Alice, Ghoumid Jamal, Guerrot Anne-Marie, Herenger Yvan, Heron Delphine, Horvath Gabriella, Ilunga Serge, Isidor Bertrand, Jeanne Médéric, Julia Sophie, Kaminska Anna, Lagrue Emmanuelle, Lambert Laetitia, Lebre Anne-Sophie, Lefranc Jérémie, Lesca Gaëtan, Levrat Virginie, Mansour Hicham, Marey Isabelle, Marret Stéphane, Maurey Hélène, Metreau Julia, Mignot Cyril, Naudion Sophie, Neveu Julien, Patat Olivier, Pasquier Laurent, Perrier Julie Boeswillwald, Petit Florence, Poulat Anne-Lise, Quélin Chloé, Richelme Christian, Rollier Paul, Rondeau Stéphane, Roubertie Agathe, Schaefer Elise, De Saint-Martin Anne, Thauvin Christel, Torre Stéphanie, Toutain Annick, Van Coster Rudy, Ville Dorothée M, Villeneuve Nathalie, Villard Laurent, Milh Mathieu
Abstract excerpt
BACKGROUND AND OBJECTIVES: Developmental and epileptic encephalopathies (DEEs) with early burst-suppression EEG (EIDEE-BS) are among the most severe neonatal epileptic syndromes, typically presenting in the first months of life with refractory seizures and profound neurodevelopmental impairment. Although variants in the KCNQ2, STXBP1, and SCN2A genes are recognized as major causes, the full genetic spectrum...
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