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Article

Phenotypic spectrum and long-term outcome of children with genetic early-infantile-onset developmental and epileptic encephalopathy.

Epileptic disorders : international epilepsy journal with videotape - 1 Apr 2022

Hu Chunhui, Liu Deying, Luo Tian, Wang Yi, Liu Zhisheng

Abstract excerpt

OBJECTIVE: Developmental and epileptic encephalopathy (DEE) is characterized by refractory seizures, developmental delay or intellectual disability, which may be caused by gene mutation. In this study, we explored the clinical phenotype and long-term outcome in children with genetic early-infantile-onset DEEs. METHODS: Next-generation sequencing was performed on 470 patients diagnosed with early-infantile-onset...

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Identifiers

PMID: 34859793
DOI: 10.1684/epd.2021.1394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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