Enhanced virulence of Autographa californica multiple nucleopolyhedrovirus in Spodoptera frugiperda is mediated by an Ac34 mutation that promotes nucleocapsid envelopment within occlusion bodies.

Abstract excerpt

Spodoptera frugiperda poses a significant threat as a polyphagous agricultural pest. Autographa californica multiple nucleopolyhedrovirus (AcMNPV), a broad-spectrum baculovirus with established activity against multiple lepidopteran pests, represents an environmentally benign biocontrol candidate. However, its efficacy against S. frugiperda is constrained by limited oral infectivity. Here, serial passaging in S....

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