Article
Potential influence of carbonic anhydrase 9 genetic variants and expression levels on the progression of diabetic retinopathy.
International journal of medical sciences - 1 Jan 2026
Liang I-Chia, Chien Hsiang-Wen, Wang Kai, Lee Chia-Yi, Chou Ying-Erh, Yang Shun-Fa
Abstract excerpt
Diabetic retinopathy (DR) represents one of the most common microvascular complications of diabetes, and proliferative diabetic retinopathy (PDR) is the most vision-threatening form. Carbonic anhydrase IX (CA9), a hypoxia-inducible enzyme, has been implicated in several pathological processes, but its involvement in DR has not been clarified. In this study, three CA9 single nucleotide polymorphisms (rs3829078,...
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