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Article

The profile of clinical and laboratory features of Chinese VEXAS syndrome patients with hematological abnormalities: a single-center case series.

Frontiers in immunology - 1 Jan 2026

Ren Xiang, Wang Min, Huo Jiali, Jia Yujiao, Xiao Jigang, Nie Neng, Huang Jinbo, Zhang Jing, Zhao Xin, Fang Liwei, Peng Guangxin, Zhang Li, Zhang Fengkui, Zheng Yizhou, Shi Jun, Ge Meili

Abstract excerpt

Objectives: VEXAS syndrome is a recently characterized hemato-inflammatory disorder caused by somatic mutations in the X-linked UBA1 gene in hematopoietic cells, which remains poorly characterized in Chinese populations. This study aims to address this gap. Methods: We retrospectively analyzed 4512 consecutive patients with hematologic abnormalities at a Chinese academic hospital between June 2023 and July 2024,...

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Identifiers

PMID: 42079602
DOI: 10.3389/fimmu.2026.1794633
PMCID: PMC13128617

Genes

UBA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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