Early pregnancy oxylipin markers of inflammation and oxidative stress are associated with small-for-gestational-age birth and specific phenotypes of fetal growth restriction.

Abstract excerpt

BACKGROUND: Fetal growth restriction places the fetus at risk for stillbirth, perinatal mortality, and severe morbidity, yet the disease remains difficult to diagnose, predict, and treat. Homeostasis of inflammation and oxidative stress is critical to the establishment of a healthy pregnancy, and biomarkers of these processes could contribute to these goals. Oxylipins are derived from polyunsaturated fatty acids...

Topics

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• Biomarkers
• Fetal Growth Retardation
• Infant, Newborn
• Infant, Small for Gestational Age