Article
Decoding the renal-cochlear axis: explainable machine learning and phenotype clustering reveal high-risk hearing loss subtypes in CKD.
Renal failure - 1 Dec 2026
Chen Ling, Wang Jing, Liu Guiqun, Zhao Yu, Zhou Zhu, Li Qing
Abstract excerpt
This study develops a dual-level machine learning framework for risk stratification and phenotyping of hearing loss (HL) in patients with chronic kidney disease (CKD) using data from the National Health and Nutrition Examination Survey (NHANES). From a cohort of 3,402 CKD patients, feature selection via univariate and multivariate logistic regression identified key predictors, which were used to construct...
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