Uncovering novel virophages and giant viruses in high-altitude Lake Namtso: diversity and evolution of host-virus-virophage tripartite interaction systems.

Abstract excerpt

Virophages are small double-stranded DNA viruses that parasitize giant viruses, modulating virus–host interactions and influencing microbial community dynamics. Despite their ecological significance, virophages and giant viruses remain poorly studied in extreme environments. Here, we present the first metagenomic survey of virophage and giant virus diversity in Lake Namtso, a high-altitude saline lake on the...

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