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Rapid and precise amplicon-based genome sequencing to preparedness and response chikungunya virus outbreaks.

Emerging microbes & infections - 1 Dec 2026

Wang Kaiying, Li Jinhui, Liu Tianyuan, Li Peihan, Wang Ning, Liu Yuqi, Liang Yufeng, Li Fenxiang, Wei Chuhong, Yan Huacheng, Li Peng

Abstract excerpt

Chikungunya virus (CHIKV) poses a significant global health threat. Effective genomic surveillance of CHIKV is critical for tracking transmission and evolution. To define an optimal framework, we systematically evaluated four next-generation sequencing (NGS) configurations combining second-generation (DNBSEQ-G99) and third-generation (QPursue-6k) chemistries with 200-bp or 400-bp amplicon schemes using 13...

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Identifiers

PMID: 41983465
DOI: 10.1080/22221751.2026.2660424
PMCID: PMC13123059

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