Article
Classification and sequencing of hepatitis D virus from a large cohort of chronically infected individuals paired with co-infecting hepatitis B virus sequencing: a genomic characterisation study.
The Lancet. Microbe - 1 May 2026
Manhas Savrina, Chang Silvia, Martin Ross, Lopez Andrew, Aeschbacher Thomas, Xu Simin, Mateo Roberto, Liu Yang, Narguet Stephanie, Abdurakhmanov Dzhamal, Lampertico Pietro, Manuilov Dmitry, Flaherty John, Mo Hongmei, Maiorova Evguenia, Asselah Tarik
Abstract excerpt
BACKGROUND: The most severe form of viral hepatitis is caused by co-infection of hepatitis D virus (HDV) and hepatitis B virus (HBV). Phylogenetic analyses classify HBV and HDV into eight major genotypes: HBV GTA to GTH and HDV GT1 to GT8. Paired HBV and HDV sequencing data from participants with chronic hepatitis delta are scarce. We aimed to sequence and genotype HDV and HBV from a large cohort of participants...
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