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Article

Outcomes of TSHR mutations in indeterminate thyroid nodules.

Cancer genetics - 1 Jun 2026

Magri Angela, Savoia Gianluca, Rutenberg Nicholas J, Avior Galit, Zarruk Alexandro, da Silva Wurzba Sabrina Daniela, Payne Richard J, Forest Véronique-Isabelle

Abstract excerpt

BACKGROUND: The thyrotropin receptor (TSHR) mutation can be present in autonomously functioning thyroid nodules (AFTNs). Our objective was to evaluate whether patients with a TSHR mutation developed AFTNs and to assess the impact of this mutation on thyroid malignancy. METHODS: We conducted a multicenter retrospective study of 1211 patients from Montreal, Canada, and from Tel Aviv, Israel, who underwent molecular...

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Identifiers

PMID: 41950860
DOI: 10.1016/j.cancergen.2026.04.003

Genes

TSHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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