Article
Red Flags for Differentiating Desmosomal "Hot-Phase" Cardiomyopathy From Acute Myocarditis.
Journal of the American Heart Association - 21 Apr 2026
Peretto Giovanni, Piriou Nicolas, Gasperetti Alessio, Bauce Barbara, Villatore Andrea, Trezza Alessia F, Melot Alex, Palmisano Anna, Bassetto Giulia, Martini Marika, Di Resta Chiara, Radesich Cinzia, Paldino Alessia, Perotto Maria, Smith Eric D, Ciabatti Michele, Bruno Elisa, De Gaspari Monica, Rizzo Stefania, Pilichou Kalliopi, Esposito Antonio, Calò Leonardo, Pieroni Maurizio, Sinagra Gianfranco, Basso Cristina, Helms Adam, Della Bella Paolo, Merlo Marco
Abstract excerpt
BACKGROUND: Desmosomal "hot-phase" cardiomyopathy (HPC), characterized by bursts of myocardial inflammation mimicking acute myocarditis (AM), carries relevant risks of adverse outcomes. This study aimed to identify diagnostic "red flags" favoring HPC over AM. METHODS: Patients (n=134) receiving a first diagnosis of AM, proven by endomyocardial biopsy or cardiac magnetic resonance plus troponin elevation, were...
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