Article
Frailty phenotype in adults with sickle cell disease.
The journals of gerontology. Series A, Biological sciences and medical sciences - 7 May 2026
Oyedeji Charity I, Mohamed Rania E, Faldowski Richard, Callaway Teagan, Poole Tamara, Denis Oliva Francyess, Mathis Veronica, Subramaniam Arvind, Whitson Heather, Reeve Bryce B, Pieper Carl, Telen Marilyn J, Ashley-Koch Allison, Cohen Harvey J, Hall Katherine, Strouse John J
Abstract excerpt
BACKGROUND: People with sickle cell disease (SCD) are at risk for accelerated biological aging and functional decline due to both age and SCD-related stressors. Frailty is characterized by decreased physiologic reserve and increased vulnerability to stressors that can lead to disability and death. The purpose of this study was to evaluate frailty phenotype in adults with SCD and identify factors associated with...
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