Article
Immune-deficient bacteria serve as gateways to genetic exchange and microbial evolution.
Nature communications - 1 Apr 2026
Figueroa Wendy, Sabnis Akshay, Ibarra-Chávez Rodrigo, Gorzynski Jamie, Fitzgerald J Ross, Penadés José R
Abstract excerpt
Horizontal gene transfer plays a key role in bacterial evolution, yet its efficiency under natural conditions, especially between genetically distinct strains, remains unclear. Using Staphylococcus aureus as a model, we found that gene transfer via various mechanisms is significantly restricted between strains from different clonal complexes (CCs), with the notable exception of lateral transduction, which occurs...
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