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Article

Multi-strain analysis of Pseudomonas putida reveals the metabolic and genetic diversity of the species.

mSystems - 21 Apr 2026

Mueller Joshua, Krishnan Jayanth, Wei Qixing, Hefner Ying, Monk Jonathan M, Verkler Hans, Tibocha-Bonilla Juan D, Ayala Anthony, Palsson Bernhard O, Feist Adam M, Niu Wei

Abstract excerpt

Pseudomonas putida is a gram-negative bacterial species increasingly utilized in biotechnology due to its robust growth, ability to degrade aromatic compounds, solvent tolerance, and genetic tractability. In this study, we report a comprehensive multi-strain analysis of 164 P. putida strains based on the reconstruction of a pan-putida metabolic network and the formulation of strain-specific genome-scale metabolic...

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Identifiers

PMID: 41919942
DOI: 10.1128/msystems.01594-25
PMCID: PMC13098254

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