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Divergent tissue tropism and pathogenicity of novel recombinant GI-19 and GI-22 infectious bronchitis virus strains.

Poultry science - 1 May 2026

Li Yuqing, Zhang Xiaolin, Zhou Ting, Yang Qingcheng, Chen Qian, Xu Ting, Yu Chunlin, Yang Chaowu, Wang Hongning, Lei Changwei, Zhang Anyun, Yang Xin

Abstract excerpt

Infectious bronchitis virus (IBV) is a highly contagious pathogen in poultry that causes significant economic losses worldwide. In this study, two novel IBV isolates, CK/CH/MY/24053 of the GI-19 lineage and CK/CH/SC/25605 of the GI-22 lineage, were isolated and analyzed through whole-genome sequencing, recombination mapping, pathogenicity assessment in SPF chickens, and S1 protein structural comparison....

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Identifiers

PMID: 41764964
DOI: 10.1016/j.psj.2026.106669
PMCID: PMC12964293

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