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Article

Ruxolitinib reverses systemic vasculitis driven by JAK2 V617F-mutated essential thrombocythemia: a case report.

Frontiers in immunology - 1 Jan 2026

Ashida Yutaro, Ota Shinji, Ishidoya Nao, Murai Yasuhisa, Amenomori Kyoko, Hasui Keisuke, Kawaguchi Shogo, Yamaguchi Satoko, Hiraga Hiroto, Kamata Kosuke, Ichikawa Hiroaki, Tomita Hirofumi, Yu Zaiqiang, Minakawa Masahito, Sakuraba Hirotake

Abstract excerpt

Background: Vasculitis associated with myeloproliferative neoplasms is rare, and reports on its treatment are limited. Herein, we report a case of Janus Kinase2 (JAK2) V617F mutation-positive essential thrombocythemia (ET) associated with vasculitis. Case presentation: A 60-year-old man with JAK2 V617F mutation-positive ET underwent coronary artery bypass grafting after recurrent myocardial infarctions and...

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Identifiers

PMID: 41909678
DOI: 10.3389/fimmu.2026.1781998
PMCID: PMC13021485

Genes

JAK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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