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Immunocompromised Status Definition in Observational Studies Using Electronic Health Records: A Scoping Review and a Proposal for a Phenotype Identification Algorithm.

Pharmacoepidemiology and drug safety - 1 Apr 2026

Riera-Arnau Judit, Luxi Nicoletta, Riefolo Fabio, Solorzano Martín, Pazos Irene, Ballarín Elena, Svingel Lise Skovgaard, Chiusaroli Lorenzo, Martín-Merino Elisa, Barbieri Elisa, Lopez-Lasanta María, Mohammadi Sima, Rotta Denis, Pacurariu Alexandra, Cohet Catherine, Sturkenboom Miriam, Durán Carlos E

Abstract excerpt

Immunocompromised individuals experience an impaired immune function due to conditions that might be either congenital or acquired over the course of their lives. Epidemiological studies often rely on clinical definitions which, in some cases, benefit from being translated into machine-readable algorithms for application to electronic health records (EHRs) databases. The transient nature of certain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41902365
DOI: 10.1002/pds.70362
PMCID: PMC13031886

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TNF

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