Article
Oligoprogression in NSCLC with Other Actionable Oncogenic Drivers Beyond EGFR and ALK: An Emerging Entity.
International journal of molecular sciences - 13 Mar 2026
Scaglione Ilaria Mariangela, Bonato Adele, Dodi Alessandra, Sposito Marco, Eccher Serena, Avancini Alice, Tregnago Daniela, Insolda Jessica, Milella Michele, Pilotto Sara, Belluomini Lorenzo
Abstract excerpt
Oligoprogressive disease (OPD) in non-small-cell lung cancer (NSCLC) is a clinical entity with peculiar behavior and treatment. OPD patients, during systemic therapy, may receive local ablative treatment (LAT) with survival benefit. The importance of OPD and the role of LAT has been comprehensively assessed in the setting of EGFR mutant and ALK-rearranged NSCLC during tyrosine kinase inhibitor (TKI) treatment,...
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