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Article

Transcriptional regulation in skeletal muscle and adipose tissue of lean and obese colony cats.

PloS one - 1 Jan 2026

Rigotti Rahel, Liesegang Annette, Dawson Holly, Brugger Daniel, Frey Diana, Samaha Georgina, Haase Bianca, Wichert Brigitta

Abstract excerpt

This study analysed gene expression profiles in white adipose and skeletal muscle tissues of cats genetically predisposed to obesity and wildtype cats to uncover molecular mechanisms regulating obesity. It also examined how these profiles altered after change in body fat through changes in the amount of food. For this purpose, 3 female cats with phenotype lean (GL) and 3 female cats with phenotype obese (GO) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41894406
DOI: 10.1371/journal.pone.0331028
PMCID: PMC13028413

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