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Errors in Germline Biomarker Testing: Significant Consequences and Missed Opportunities for Cancer Control in Patients and Their Families.

Cancer journal (Sudbury, Mass.) - 1 Jan 2026

Mahon Suzanne M, McLaughlin Laura A, Khemthong Usa, Owen Constance

Abstract excerpt

PURPOSE: Germline biomarker testing to assess inherited risk for developing malignancy has evolved quickly from testing for 1 or 2 genes from a few laboratories to ordering panels of 80 or more genes available from multiple laboratories. Many health professionals did not receive foundational information in training yet are expected to identify and manage care for individuals and families with germline risk....

Topics

Humans
Genetic Testing
Germ-Line Mutation
Neoplasms
Biomarkers, Tumor
Genetic Predisposition to Disease
Diagnostic Errors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 41880262
DOI: 10.1097/PPO.0000000000000812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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