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Article

Decoding Adipose Tissue Phenotypic Switching: From Mechanisms to Computational Drug Discovery.

Current obesity reports - 23 Mar 2026

Ye Yuqing, Yin Ruxin, Sun Junjie, Dai Yuwei, Zhao Di, Zou Xiaoling

Abstract excerpt

PURPOSE OF REVIEW: This review aims to explore the therapeutic potential of brown adipose tissue (BAT) to combat obesity and associated metabolic disorders by synthesizing the multifactorial influences and underlying mechanisms of BAT whitening and employing computational screening to identify promising candidate molecules for further investigation. RECENT FINDINGS: BAT whitening is characterized by the loss of...

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Identifiers

PMID: 41866446
DOI: 10.1007/s13679-026-00701-y
PMCID: PMC13006473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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