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Article

Genetic, epigenetic and metabolite variation in peripheral European Yew (Taxus baccata L.) populations at an unexplored part of the species natural distribution.

PloS one - 1 Jan 2026

Dalmaris Eleftheria, Avramidou Evangelia, Sarrou Eirini, Xanthopoulou Aliki, Multari Salvatore, Martens Stefan, Aravanopoulos Filippos A

Abstract excerpt

Taxanes form effective anticancer agents, which are found in the leaves and bark of the yew tree (Taxus L.). Paclitaxel (Taxol®) and related taxanes are widely used in cancer therapy. Due to the high demand of taxanes, there is strong pharmaceutical interest in evaluating unexplored population diversity as a potential genetic and biochemical resource. Three peripheral Greek Taxus baccata L. populations (Mt...

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PMID: 41860850
DOI: 10.1371/journal.pone.0324582
PMCID: PMC13004391

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