Article
SdLDL‑C/LDL‑C discordance as a practical surrogate for triglyceride‑associated cardiovascular risk: identification of at‑risk lipid phenotypes in the CHARLS prospective cohort.
Lipids in health and disease - 18 Mar 2026
Xue Yaya, Luo Jing, Yang Xinyu, Ren Zhaoyu, Fan Hongxuan, Luo Wei, Liang Bin
Abstract excerpt
BACKGROUND: Discordance between small dense low-density lipoprotein cholesterol (sdLDL-C) and low-density lipoprotein cholesterol (LDL-C) levels is common. Whether this easily calculated parameter, derived from routine lipid profiles using the triglyceride (TG)-dependent Sampson equation, can serve as a practical surrogate for TG-associated cardiovascular disease (CVD) risk and improve risk stratification remains...
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