Article
Large-scale multi-omics profiling reveals environmental and evolutionary drivers of fungal phylogeographic and metabolic diversity.
Nature communications - 18 Mar 2026
Xie Huali, Hu Jie, Zhao Xiulan, Chen Jianwei, Yue Xiaofeng, Zhou Changhao, Navarro-Muñoz Jorge C, Jiang Jun, Tang Xiaoqian, Zhao Fang, Hatmaker E Anne, Rokas Antonis, Barber Amelia E, Drott Milton T, Keller Nancy P, Zhang Qi, van der Hooft Justin J J, Medema Marnix H, Li Peiwu
Abstract excerpt
Chemical innovation is essential for fungi to adapt to ever-changing ecological environments. However, the environmental and evolutionary drivers of fungal metabolic differentiation remain ambiguous. Here, we show the phylogeographic diversity of 1052 Aspergillus flavus strains across four continents, as conducted through phylogenetic and biogeographical analysis, including 544 newly sequenced strains from China....
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