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Article

Association Between Inflammatory Bowel Disease and Venous Leg Ulcers: Insight From Mendelian Randomization Analyses.

Canadian journal of gastroenterology & hepatology - 1 Jan 2026

Lin Yanfeng, Qin Xiaohui, Zhang Haiyan, Huang Jinke

Abstract excerpt

BACKGROUND: This study aimed to investigate the potential causal relationship between inflammatory bowel disease (IBD) and venous leg ulcers (VLU) using Mendelian randomization (MR). MATERIALS AND METHODS: Independent genetic variants for IBD and VLU were selected as instruments from previously published genome-wide association studies (GWAS) in people of primarily European descent. MR analyses were carried out...

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PMID: 41811798
DOI: 10.1155/cjgh/6767725

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