Analysis of CYLD gene variants in 41 patients with multiple familial trichoepithelioma.

doi:10.1111/ddg.70013

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Article

Analysis of CYLD gene variants in 41 patients with multiple familial trichoepithelioma.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG - 1 Sept 2026

Cui Mengxing, Zheng Liyun, Zhang Yue, Zhang Guiyuan, Qin Sijia, Chen Gang, Liang Bo

Abstract excerpt

OBJECTIVE: To investigate the variants of the CYLD gene in Chinese patients with multiple familial trichoepithelioma (MFT), aiming to provide a scientific basis for genetic counseling and prenatal diagnosis, thereby creating favorable conditions for intervention treatment and improving the prognosis of patients. PATIENTS AND METHODS: Whole-exome sequencing (WES) was performed in patients from eleven families to...

Read the complete abstract on PubMed

Topics

Humans
Deubiquitinating Enzyme CYLD
Female
Male
Neoplastic Syndromes, Hereditary
Skin Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adult

Genetic Predisposition to Disease

Pedigree

Middle Aged

Adolescent

Young Adult

DNA Mutational Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 41810882
DOI: 10.1111/ddg.70013
PMCID: PMC13551202

Genes

CYLD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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Analysis of CYLD gene variants in 41 patients with multiple familial trichoepithelioma.PMID 41810882Read ↗

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Three mutations of CYLD gene in Chinese families with multiple familial trichoepithelioma.Semantic proximity Read ↗

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