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Article

A novel splicing mutation of the CYLD gene in a Taiwanese family with multiple familial trichoepithelioma.

Clinical and experimental dermatology - 1 Jan 2009

Huang T-M, Chao S-C, Lee J Y-Y

Abstract excerpt

Multiple familial trichoepithelioma (MFT) is an autosomal dominant disease characterized by numerous skin-coloured papules on the central face. Mutations in the CYLD gene, which is also the gene responsible for familial cylindromatosis, have been reported recently. Recent studies indicate that CYLD is a tumour-suppressor gene. The CYLD protein is a negative regulator of the activation of transcription factor...

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Source

Identifiers

PMID: 19076795
DOI: 10.1111/j.1365-2230.2008.02870.x

Genes

CYLD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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