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Article

Extracellular vesicles related to familial hypercholesterolemia.

Archives of endocrinology and metabolism - 1 Apr 2026

Silvino Júnea P de P, Jannes Cinthia E, Pestana Rodrigo M C, Silvino Lucas P de P, Silva Iêda de F O, Teixeira-Carvalho Andréa, Gomes Karina B

Abstract excerpt

OBJECTIVE: This study aimed to evaluate extracellular vesicles (EVs) in a group of carriers of familial hypercholesterolemia (FH)-related genetic variants compared to those in family members without FH. SUBJECTS AND METHODS: Annexin V-positive EVs (PS+-EVs), cardiomyocyte-derived EVs (CardioEVs), endothelial cell-derived EVs (EEVs), platelet-derived EVs (PEVs) and tissue factor-expressing EVs (TFEVs) were...

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Topics

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Share to Blood Platelets
Share to Cholesterol, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelial Cells

Share to Extracellular Vesicles

Share to Genetic Variation

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Hyperlipoproteinemia Type II

Share to Myocytes, Cardiac

Source

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Identifiers

PMID: 41805290
DOI: 10.20945/2359-4292-2026-0022
PMCID: PMC12977345

Genes

FH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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