Article
Engineering glyphosate tolerance in sugarcane through overexpression of a mutated version of its native EPSPS gene.
GM crops & food - 1 Dec 2026
Alves Pâmela Ingrid, Heleodoro Talita, Spinassé Floreste Bruno, Moreira Neris Daniel, Silvério Pena Bento João Pedro, Smith Bradley J, de Rezende Fernanda Mendes, Pinoti Vitor, de Lucca Paulo Cézar, da Silva Jovanderson Jackson Barbosa, Falsarella Carazzolle Marcelo, Amarante Guimarães Pereira Gonçalo, Mazzafera Paulo, Lischka Sampaio Mayer Juliana, Silveira Buckeridge Marcos, Menossi Marcelo
Abstract excerpt
Sugarcane is a globally important crop, widely used in both the food industry and biofuel production. Weed infestations can significantly reduce its productivity, and to address this challenge, herbicides such as glyphosate are commonly applied. Glyphosate acts as a structural analog of phosphoenolpyruvate (PEP), inhibiting the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), thereby disrupting the...
Topics
- Saccharum
- Glycine
- Glyphosate
- 3-Phosphoshikimate 1-Carboxyvinyltransferase
- Plants, Genetically Modified
- Herbicides
- Herbicide Resistance
- Mutation