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Article

MMP-8 in Peri-Implantitis: A Cross-Sectional Study on Genetic Polymorphisms and Enzymatic Activation.

Journal of periodontal research - 1 Jan 2026

Fragkioudakis Ioannis, Kottaridi Christine, Paraskeva Michalis, Sakellari Dimitra

Abstract excerpt

This graphical abstract illustrates a molecular cascade linking MMP-8 gene polymorphism (-799C/T), upregulated mRNA expression in peri-implant crevicular fluid, and elevated active MMP-8 protein levels. These factors were independently associated with peri-implantitis and may support molecular-based diagnostics.

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Identifiers

PMID: 41782448
DOI: 10.1111/jre.70026
PMCID: PMC12961359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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