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Migraine is Related to Multiple Sclerosis Brain Lesions in the Central Pain Network with Several Migraine Phenotypes Exhibiting Different Lesion Patterns.

Brain topography - 4 Mar 2026

Fröhlich Kilian, Macha Kosmas, Krämer Matthias, Haupenthal David, Sekita Alexander, Dörfler Arnd, Winder Klemens, Mrochen Anne

Abstract excerpt

Migraine is a frequent and debilitating comorbidity in multiple sclerosis (MS). Migraine headache and concomitant symptoms might be just coincidental or due to inflammatory MS activity, which is highly relevant for patients. Headache in general has been shown to be attributed to inflammatory cerebral MS lesions in the central pain matrix. The question whether migraine headache is associated with a different...

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Identifiers

PMID: 41779223
DOI: 10.1007/s10548-026-01182-x
PMCID: PMC12960446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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