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Evolutionary and Modification Features of Two Monkeypox Virus Strains: Insights from Integrated Genomic and Epigenomic Analyses.

Viruses - 18 Feb 2026

Zhao Zhongru, Zhang Bohan, Han Jingwan, Lin Dandan, Liu Yongjian, Jia Lei, Li Hanping, Li Jingyun, Wang Xiaolin, Wen Hongling, Li Lin

Abstract excerpt

Since 2022, global outbreaks of monkeypox virus (MPXV) have been repeatedly designated by the World Health Organization (WHO) as a public health emergency of international concern (PHEIC), underscoring the urgent need to elucidate the multidimensional mechanisms underlying viral evolution and transmission. Current understanding remains largely focused on genomic variation, while the critical role of epigenetic...

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Identifiers

PMID: 41754602
DOI: 10.3390/v18020259
PMCID: PMC12944984

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