Associations Between Obesity, Diabetes Mellitus, and Pancreatic Cancer in the Japanese Population: A Mendelian Randomization Study.

doi:10.1111/cas.70344

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Associations Between Obesity, Diabetes Mellitus, and Pancreatic Cancer in the Japanese Population: A Mendelian Randomization Study.

Cancer science - 1 May 2026

Lin Yingsong, Sasado Haruki, Sasahira Naoki, Ueno Makoto, Ishii Hiroshi, Egawa Naoto, Adachi Yasushi, Ozaka Masato, Kobayashi Satoshi, Koyanagi Yuriko N, Yamamoto Sayaka, Ito Hidemi, Narita Akira, Sakurai-Yageta Mika, Okusaka Takuji, Kuchiba Aya, Yoshida Teruhiko, Matsuda Fumihiko, Kamatani Yoichiro, Nakano Shiori, Yamaji Taiki, Sawada Norie, Kadota Aya, Kuriki Kiyonori, Watanabe Takeshi, Fuse Nobuo, Kinoshita Kengo, Nakaya Naoki, Sutoh Yoichi, Otsuka-Yamasaki Yayoi, Tanno Kozo, Suzuki Ken, Yamauchi Toshimasa, Kadowaki Takashi, Iwasaki Motoki, Nakamura Sho, Hozawa Atsushi, Shimizu Atsushi, Kikuchi Shogo, Nakatochi Masahiro, Matsuo Keitaro

Abstract excerpt

The association between body mass index (BMI) and pancreatic cancer remains elusive in Asian populations. Clarifying the causal relationship between type 2 diabetes (T2D) and pancreatic cancer warrants triangulation of evidence, with Mendelian Randomization (MR) providing a robust approach. A two-sample, multivariable MR analysis was performed to investigate the associations between BMI, T2D, and pancreatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Diabetes Mellitus, Type 2

Share to East Asian People

Share to Japan

Share to Mendelian Randomization Analysis

Share to Obesity

Share to Odds Ratio

Share to Pancreatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 41709847
DOI: 10.1111/cas.70344
PMCID: PMC13134504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations Between Obesity, Diabetes Mellitus, and Pancreatic Cancer in the Japanese Population: A Mendelian Randomization Study.PMID 41709847Read ↗

Strengthening the Evidence for a Causal Link between Type 2 Diabetes Mellitus and Pancreatic Cancer: Insights from Two-Sample and Multivariable Mendelian Randomization.Semantic proximity Read ↗

Coffee and Risk of Pancreatic Cancer: Insights from Two-Sample and Multivariable Mendelian Randomization Analyses.Semantic proximity Read ↗

Diabetes Mellitus and Pancreatic Cancer: Investigation of Causal Pathways Through Mendelian Randomization AnalysisSemantic proximity Read ↗

Diabetes and cancer risk: A Mendelian randomization studySemantic proximity Read ↗

The Role of Obesity, Type 2 Diabetes, and Metabolic Factors in Pancreatic Cancer: A Mendelian Randomization Study.Semantic proximity Read ↗

Causal relationship between body mass index and insulin resistance: Linear and nonlinear Mendelian randomization study in a Japanese populationSemantic proximity Read ↗

Association between diabetes mellitus and primary biliary cholangitis: a two-sample Mendelian randomization study.Semantic proximity Read ↗

Association of Body Mass Index and the Risk of Gastro-Esophageal Cancer: A Mendelian Randomization Study in a Japanese Population.Semantic proximity Read ↗

Causal linkage between type 2 diabetes mellitus and inflammatory bowel disease: an integrated Mendelian randomization study and bioinformatics analysisSemantic proximity Read ↗

Exploring the causality and pathogenesis of Type 2 diabetes in gastric cancer based on Mendelian randomization and transcriptome data analysesSemantic proximity Read ↗

Body mass index and colorectal cancer risk: A Mendelian randomization study.Semantic proximity Read ↗

Body mass index, C-reactive protein, and pancreatic cancer: A Mendelian randomization analysis to investigate causal pathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.