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Article

A lateralized sensory signaling pathway mediates context-dependent olfactory plasticity in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 24 Feb 2026

Pandey Anjali, Katz Maya, Nurrish Stephen, Philbrook Alison, Sengupta Piali

Abstract excerpt

Lateralization of neuronal functions plays a critical role in regulating behavioral flexibility, but the underlying molecular mechanisms are challenging to establish at a single-neuron level. We previously showed that attraction of Caenorhabditis elegans to a medium-chain alcohol switches to avoidance in a uniform background of a second attractive odorant. This context-dependent behavioral plasticity is mediated...

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Identifiers

PMID: 41701822
DOI: 10.1073/pnas.2519437123
PMCID: PMC12915687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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