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Article

Towards an objective classification of pachychoroid disease and its risk of progression.

Eye (London, England) - 1 Apr 2026

Cicinelli Maria Vittoria, Bianco Lorenzo, Caminada Lorenzo, Barlocci Eugenio, Giuffré Chiara, De Carlo Maria Pia, Chhablani Jay, Introini Ugo, Bandello Francesco

Abstract excerpt

PURPOSE: To identify clinical phenotypes in pachychoroid disease (PD), characterise long-term progression patterns, and evaluate the effect of photodynamic therapy (PDT) using machine learning and longitudinal probabilistic modelling. METHODS: This retrospective cohort study included 973 eyes from 663 patients (mean age 54.4 ± 12.8 years; 80% male) diagnosed with PD. Eyes were classified based on macular fluid...

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Identifiers

PMID: 41699162
DOI: 10.1038/s41433-026-04286-7
PMCID: PMC13062073

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