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Phenotypic and genomic characterization of NDM-producing Escherichia coli colonizing the pediatric gut in Shenzhen, China.

Microbiology spectrum - 7 Apr 2026

He Yunxing, Yang Hongmei, Liao Cuimei, Ou Xiaoying, Yang Kaiyue, Ding Tongyan, Zhou Xiaojie, Liu Xiuju, Liu Shuyan, Zhou Zhenwen, Chen Tingjin

Abstract excerpt

Carbapenem-resistant Enterobacterales, driven by New Delhi metallo-β-lactamases (NDMs), severely restrict treatment options and are increasingly detected outside hospitals. Yet, integrated genomic-phenotypic data on NDM-positive Escherichia coli colonizing the pediatric gut in China remain scarce. Antimicrobial susceptibility and blaNDM conjugation were tested. Whole-genome sequencing (WGS) profiled the...

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Identifiers

PMID: 41685987
DOI: 10.1128/spectrum.03329-25
PMCID: PMC13055255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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