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Article

Efficacy of phosphonium amphiphilic salts against Acanthamoeba genotype T4.

International journal for parasitology. Drugs and drug resistance - 1 Apr 2026

Lukáč Miloš, Pisárčik Martin, Garajová Mária, Walochnik Julia, Ošustová Daniela, Vatrtová Eva, Bondar Iryna, Devínsky Ferdinand, Mrva Martin

Abstract excerpt

Acanthamoebae are opportunistic pathogens causing serious human infections, including granulomatous amoebic encephalitis (GAE) and Acanthamoeba keratitis (AK). The treatment of those infections is limited and difficult to date. Recent research demonstrated high antimicrobial activity of phosphonium amphiphilic salts. In the present work we aimed to investigate the anti-Acanthamoeba effect of a series of 16...

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Identifiers

PMID: 41655451
DOI: 10.1016/j.ijpddr.2026.100636
PMCID: PMC12907838

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