Article
The emergence and spread of a novel sequence type of Corynebacterium diphtheriae in Vietnam.
Scientific reports - 6 Feb 2026
Hoang Le Huy, Hoa Luong Minh, Hai Pham Thanh, Ngoc Do Bich, Thang Nguyen Tat, Ly Phan Thao, Nguyen Phuong Thi Lan, Lan Phan Trong, Duong Tran Nhu, Huong Nguyen Thi Thanh, Morita Masatomo, Ha Hoang Thi Thu, Senoh Mitsutoshi
Abstract excerpt
Diphtheria remains a public health concern in Vietnam. This study used whole-genome sequencing to characterize the genetic diversity, virulence, and antimicrobial resistance profiles of 21 Corynebacterium diphtheriae isolates collected from 2013 to 2024. Phylogenetic relationships were determined using core-genome MLST (cgMLST) and SNP analysis. AMR was assessed via phenotypic testing (CLSI/EUCAST standards) and...
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