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Article

Age-specific vaginal microecological dysbiosis associated with HPV infection: a large-scale cross-sectional study with targeted functional sequencing validation.

Frontiers in cellular and infection microbiology - 1 Jan 2025

Wang Yue, Chen HongJing, Chen YaoJia, Lu YanFang, Wei BiNa, Wu ZhiHui, Gao HangJing, Feng LuLu, Xie Fang, Li Qing, Lin WenYu, Sun XiaoQi, Lin Hao, Dong BinHua, Sun PengMing

Abstract excerpt

Purpose: The vaginal microecological parameters as a critical immune barrier, yet their age-dependent interaction with Human papillomavirus (HPV) infection remains poorly understood. To characterize age-dependent vaginal microbiota composition and function across the female lifespan, and to evaluate the selective impact of HPV infection on microecological stability and infectious risk. Methods: A total of 23,672...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41647262
DOI: 10.3389/fcimb.2025.1722367
PMCID: PMC12868268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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