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Article

Causal validation of immune antibody responses and nonalcoholic fatty liver disease: Evidence from Mendelian randomization and meta-analysis.

Medicine - 30 Jan 2026

Zhao Zhengyi, Guo Yitao, Hong Shihao, Miao Linzhe

Abstract excerpt

In recent years, an increasing number of observational studies have reported the influence of immunity and antibodies on nonalcoholic fatty liver disease (NAFLD). However, no Mendelian randomization (MR) studies have yet been conducted to investigate the causal relationship in NAFLD. Based on a 2-sample MR framework, this study conducted MR analyses between 46 antibody immune response phenotypes and NAFLD using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41630277
DOI: 10.1097/MD.0000000000047386
PMCID: PMC12863889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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