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Transcriptome integration analysis of shared biomarkers and common immune mechanisms in SLE and PSO.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2026

Cheng Meijia, Pei Yue, Li Baoyue, Yu Yanhui, Li Jiangning, Zhang Jingyan, Sun Xiaodong, Zou Dan, Liu Yunen, Wang Yichen

Abstract excerpt

This study aimed to identify shared diagnostic biomarkers and common immune mechanisms between systemic lupus erythematosus (SLE) and psoriasis (PSO) via integrated transcriptomic analysis, and to elucidate the role of genetic susceptibility in driving disease pathogenesis following viral infection. GEO datasets of SLE and PSO were analyzed. Shared genes were screened using differential expression analysis and...

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Gene Expression Profiling
Biomarkers
Gene Regulatory Networks
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lupus Erythematosus, Systemic

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Identifiers

PMID: 41577004
DOI: 10.1016/j.meegid.2026.105886

Genes

SAMD9
UBE2L6
IFI6
MX1
NMI
OAS3
OASL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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