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Article

Charcot-Marie-Tooth disease and related neuropathies.

Nature reviews. Disease primers - 22 Jan 2026

Burns Joshua, Timmerman Vincent, Laurá Matilde, Yiu Eppie M, D'Antonio Maurizio, Mukherjee-Clavin Bipasha, De Winter Jonathan, Scherer Steven S

Abstract excerpt

Charcot-Marie-Tooth disease (CMT) subsumes many different inherited neuropathies. CMT and related neuropathies are among the most common inherited neurological disorders, affecting ~1 in 2,500 people globally and including both sexes. Mutations in genes that cause demyelinating forms of CMT often affect the proteins of the myelin sheath, the unfolded protein response, endosomal signalling and recycling, or key...

Topics

Humans
Charcot-Marie-Tooth Disease
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 41571707
DOI: 10.1038/s41572-025-00679-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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