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Mild Thalassemic Effect of Heterozygous Hb Sogn in a Large Cohort from Routine Hemoglobinopathy Investigation.

Hemoglobin - 1 Jan 2026

Fjeld Bente, Jørgensen Markus, Lillemoen Paul Kjetel Soldal, Holstad Kristin, Klingenberg Olav

Abstract excerpt

Hemoglobin (Hb) Sogn is a rare Hb variant discovered in Norwegians and their descendants. Previous reports suggested no clinical symptoms in the heterozygote, but mild in vitro instability of the variant. Our recent clinical observations prompted suspicion of mild hematological abnormalities. This study aimed to evaluate hematological parameters and Hb fractions in individuals heterozygous for Hb Sogn, compared...

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Identifiers

PMID: 41558986
DOI: 10.1080/03630269.2026.2613682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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