Article
Molecular characterization of hemoglobin D Punjab traits and clinical-hematological profile of the patients.
Sao Paulo medical journal = Revista paulista de medicina - 1 Jan 2012
Pandey Sanjay, Mishra Rahasya Mani, Pandey Sweta, Shah Vineet, Saxena Renu
Abstract excerpt
CONTEXT AND OBJECTIVE: Hemoglobin (Hb) D hemoglobinopathies are widespread diseases in northwestern India and usually present with mild hemolytic anemia and mild to moderate splenomegaly. The heterozygous form of Hb D is clinically silent, but coinheritance of Hb D with Hb S or beta-thalassemia produces clinically significant conditions like thalassemia intermedia of moderate severity. Under heterozygous...
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