Article
Multi-omics reveals co-regulation of hepatic bile acid metabolism in laying hens by host genetics and the cecal Anaerostipes.
Poultry science - 1 Mar 2026
Yang Wenwei, Zhao Yang, Liu Xinxin, Cai Yuanrong, Dai Yuchi, Zhang Hanqi, Chen Yuqing, Chen Feifan, Liu Fei, Sun Congjiao, Yang Ning, Yan Wei
Abstract excerpt
Bile acids (BA) are central regulators of lipid metabolism and key signaling molecules within the gut-liver axis. Dysregulation of BA is implicated in fatty liver hemorrhagic syndrome (FLHS), a prevalent metabolic disorder in laying hens characterized by hepatic lipid accumulation, hemorrhage, reduced egg production, and increased mortality. However, the mechanisms governing BA regulation in poultry remain poorly...
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